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IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?
Insulin-like growth factors (IGFs) are key growth-promoting peptides that act as both endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local tissues, most IGF molecules are bound by one of the members of the IGF-binding protein (IGFBP) family, of which six distinc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900387/ https://www.ncbi.nlm.nih.gov/pubmed/29686648 http://dx.doi.org/10.3389/fendo.2018.00117 |