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Low Cerebrospinal Fluid Aβ(42) and Aβ(40) are Related to White Matter Lesions in Cognitively Normal Elderly

BACKGROUND: Low cerebrospinal fluid (CSF) levels of Aβ(42) may be the earliest manifestation of Alzheimer’s disease (AD). Knowledge on how CSF Aβ interacts with different brain pathologies early in the disease process is limited. We examined how CSF Aβ markers relate to brain atrophy and white matte...

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Detalles Bibliográficos
Autores principales: Skoog, Ingmar, Kern, Silke, Zetterberg, Henrik, Östling, Svante, Börjesson-Hanson, Anne, Guo, Xinxin, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900552/
https://www.ncbi.nlm.nih.gov/pubmed/29614655
http://dx.doi.org/10.3233/JAD-170950