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Hydrolytic activity of human Nudt16 enzyme on dinucleotide cap analogs and short capped oligonucleotides

Human Nudt16 (hNudt16) is a member of the Nudix family of hydrolases, comprising enzymes catabolizing various substrates including canonical (d)NTPs, oxidized (d)NTPs, nonnucleoside polyphosphates, and capped mRNAs. Decapping activity of the Xenopus laevis (X29) Nudt16 homolog was observed in the nu...

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Detalles Bibliográficos
Autores principales: Grzela, Renata, Nasilowska, Karolina, Lukaszewicz, Maciej, Tyras, Michal, Stepinski, Janusz, Jankowska-Anyszka, Marzena, Bojarska, Elzbieta, Darzynkiewicz, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900562/
https://www.ncbi.nlm.nih.gov/pubmed/29483298
http://dx.doi.org/10.1261/rna.065698.118