Cargando…

Tudor staphylococcal nuclease is a structure-specific ribonuclease that degrades RNA at unstructured regions during microRNA decay

Tudor staphylococcal nuclease (TSN) is an evolutionarily conserved ribonuclease in eukaryotes that is composed of five staphylococcal nuclease-like domains (SN1–SN5) and a Tudor domain. TSN degrades hyper-edited double-stranded RNA, including primary miRNA precursors containing multiple I•U and U•I...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chia-Lung, Yang, Wei-Zen, Shi, Zhonghao, Yuan, Hanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900569/
https://www.ncbi.nlm.nih.gov/pubmed/29440319
http://dx.doi.org/10.1261/rna.064501.117