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A bone marrow niche-derived molecular switch between osteogenesis and hematopoiesis

Hematopoietic stem cells (HSCs) reside and are maintained in specialized microenvironments within the bone marrow known as niches, which are comprised of various cell types. Among them, leptin receptor (LepR)-expressing CXC chemokine ligand 12 (CXCL12)-abundant reticular (CAR) cells are known to cre...

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Detalles Bibliográficos
Autores principales: Galán-Díez, Marta, Kousteni, Stavroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900706/
https://www.ncbi.nlm.nih.gov/pubmed/29593065
http://dx.doi.org/10.1101/gad.314013.118