Cooperative recruitment of Yan via a high-affinity ETS supersite organizes repression to confer specificity and robustness to cardiac cell fate specification

Cis-regulatory modules (CRMs) are defined by unique combinations of transcription factor-binding sites. Emerging evidence suggests that the number, affinity, and organization of sites play important roles in regulating enhancer output and, ultimately, gene expression. Here, we investigate how the ci...

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Detalles Bibliográficos
Autores principales: Boisclair Lachance, Jean-François, Webber, Jemma L., Hong, Lu, Dinner, Aaron R., Rebay, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900712/
https://www.ncbi.nlm.nih.gov/pubmed/29535190
http://dx.doi.org/10.1101/gad.307132.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900712/
https://www.ncbi.nlm.nih.gov/pubmed/29535190
http://dx.doi.org/10.1101/gad.307132.117

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