The glycan‐dependent ERAD machinery degrades topologically diverse misfolded proteins

Many soluble and integral membrane proteins fold in the endoplasmic reticulum (ER) with the help of chaperones and folding factors. Despite these efforts, protein folding is intrinsically error prone and amino acid changes, alterations in post‐translational modifications or cellular stress can cause...

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Detalles Bibliográficos
Autores principales: Shin, Yun‐Ji, Vavra, Ulrike, Veit, Christiane, Strasser, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900737/
https://www.ncbi.nlm.nih.gov/pubmed/29396984
http://dx.doi.org/10.1111/tpj.13851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900737/
https://www.ncbi.nlm.nih.gov/pubmed/29396984
http://dx.doi.org/10.1111/tpj.13851

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