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Anticancer Effects of Gingerol in Retinoblastoma Cancer Cells (RB355 Cell Line) Are Mediated via Apoptosis Induction, Cell Cycle Arrest and Upregulation of PI3K/Akt Signaling Pathway

BACKGROUND: The main aim of the current investigation was to study the antiproliferative activity of gingerol in RB355 human retinoblastoma cancer cells. The effects of gingerol on apoptosis induction, cell cycle arrest, and PI3K/Akt signaling pathway were also evaluated. MATERIAL/METHODS: MTT cell...

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Detalles Bibliográficos
Autores principales: Meng, Bo, Ii, Hongyi, Qu, Wei, Yuan, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900802/
https://www.ncbi.nlm.nih.gov/pubmed/29615601
http://dx.doi.org/10.12659/MSM.905450