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Adult spinal opioid receptor μ1 expression after incision is altered by early life repetitive tactile and noxious procedures in rats

Clinical and experimental data suggests that noxious stimulation at critical stages of development results in long‐term changes on nociceptive processing in later life. Here, we use an established, well‐documented rat model of repetitive noxious procedures closely mimicking the clinical situation in...

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Detalles Bibliográficos
Autores principales: van den Hoogen, Nynke J., van Reij, Roel RI, Patijn, Jacob, Tibboel, Dick, Joosten, Elbert A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900868/
https://www.ncbi.nlm.nih.gov/pubmed/29473323
http://dx.doi.org/10.1002/dneu.22583