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Adult spinal opioid receptor μ1 expression after incision is altered by early life repetitive tactile and noxious procedures in rats
Clinical and experimental data suggests that noxious stimulation at critical stages of development results in long‐term changes on nociceptive processing in later life. Here, we use an established, well‐documented rat model of repetitive noxious procedures closely mimicking the clinical situation in...
Autores principales: | van den Hoogen, Nynke J., van Reij, Roel RI, Patijn, Jacob, Tibboel, Dick, Joosten, Elbert A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900868/ https://www.ncbi.nlm.nih.gov/pubmed/29473323 http://dx.doi.org/10.1002/dneu.22583 |
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