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Establishing upper limits on neuronal activity–evoked pH changes with APT‐CEST MRI at 7 T

PURPOSE: To detect neuronal activity–evoked pH changes by amide proton transfer–chemical exchange saturation transfer (APT‐CEST) MRI at 7 T. METHODS: Three healthy subjects participated in the study. A low‐power 3‐dimensional APT‐CEST sequence was optimized through the Bloch‐McConnell equations. pH...

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Detalles Bibliográficos
Autores principales: Khlebnikov, Vitaliy, Siero, Jeroen C.W., Bhogal, Alex A., Luijten, Peter R., Klomp, Dennis W.J., Hoogduin, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900917/
https://www.ncbi.nlm.nih.gov/pubmed/29154463
http://dx.doi.org/10.1002/mrm.27013