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Age‐associated changes in the blood‐brain barrier: comparative studies in human and mouse

AIMS: While vascular pathology is a common feature of a range of neurodegenerative diseases, we hypothesized that vascular changes occur in association with normal ageing. Therefore, we aimed to characterize age‐associated changes in the blood–brain barrier (BBB) in human and mouse cohorts. METHODS:...

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Detalles Bibliográficos
Autores principales: Goodall, E. F., Wang, C., Simpson, J. E., Baker, D. J., Drew, D. R., Heath, P. R., Saffrey, M. J., Romero, I. A., Wharton, S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900918/
https://www.ncbi.nlm.nih.gov/pubmed/28453876
http://dx.doi.org/10.1111/nan.12408