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A General Strategy to Access Structural Information at Atomic Resolution in Polyglutamine Homorepeats

Homorepeat (HR) proteins are involved in key biological processes and multiple pathologies, however their high‐resolution characterization has been impaired due to their homotypic nature. To overcome this problem, we have developed a strategy to isotopically label individual glutamines within HRs by...

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Detalles Bibliográficos
Autores principales: Urbanek, Annika, Morató, Anna, Allemand, Frédéric, Delaforge, Elise, Fournet, Aurélie, Popovic, Matija, Delbecq, Stephane, Sibille, Nathalie, Bernadó, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901001/
https://www.ncbi.nlm.nih.gov/pubmed/29359503
http://dx.doi.org/10.1002/anie.201711530