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Role of Polymorphonuclear Leukocytes in the Pathophysiology of Typical Hemolytic Uremic Syndrome

Thrombotic microangiopathy and acute renal failure are cardinal features of post-diarrheal hemolytic uremic syndrome (HUS). These conditions are related to endothelial and epithelial cell damage induced by Shiga toxin (Stx), through an interaction with its globotriaosylceramide (Gb(3)) receptor. Alt...

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Detalles Bibliográficos
Autores principales: Exeni, Ramón A., Fernández, Gabriela C., Palermo, Marina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901139/
https://www.ncbi.nlm.nih.gov/pubmed/17694250
http://dx.doi.org/10.1100/tsw.2007.172