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Intracellular Targeting of CEA Results in Th1-Type Antibody Responses Following Intradermal Genetic Vaccination by a Needle-Free Jet Injection Device

The route and method of immunization, as well as the cellular localization of the antigen, can influence the generation of an immune response. In general, intramuscular immunization results in Th1 responses, whereas intradermal delivery of DNA by gene gun immunization often results in more Th2 respo...

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Detalles Bibliográficos
Autores principales: Johansson, Susanne, Ek, Monica, Wahren, Britta, Stout, Richard, Liu, Margaret A., Hallermalm, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901223/
https://www.ncbi.nlm.nih.gov/pubmed/17619780
http://dx.doi.org/10.1100/tsw.2007.138