Opioid-Induced Glial Activation: Mechanisms of Activation and Implications for Opioid Analgesia, Dependence, and Reward

This review will introduce the concept of toll-like receptor (TLR)–mediated glial activation as central to all of the following: neuropathic pain, compromised acute opioid analgesia, and unwanted opioid side effects (tolerance, dependence, and reward). Attenuation of glial activation has previously...

Descripción completa

Detalles Bibliográficos
Autores principales: Hutchinson, Mark R., Bland, Sondra T., Johnson, Kirk W., Rice, Kenner C., Maier, Steven F., Watkins, Linda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2007
Materias:
Mini-Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901235/
https://www.ncbi.nlm.nih.gov/pubmed/17982582
http://dx.doi.org/10.1100/tsw.2007.230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901235/
https://www.ncbi.nlm.nih.gov/pubmed/17982582
http://dx.doi.org/10.1100/tsw.2007.230

Ejemplares similares