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The Role of 5-Lipoxygenase and Leukotrienes in Shock and Ischemia-Reperfusion Injury

The leukotrienes (LTs) are metabolic products of arachidonic acid via the 5-lipoxygenase (5-LO) pathway. The biological activities of LTs suggest that they are mediators of acute inflammatory and immediate hypersensitivity responses. In particular, the 5-LO activation has been proposed to be an impo...

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Detalles Bibliográficos
Autores principales: Rossi, Antonietta, Pergola, Carlo, Cuzzocrea, Salvatore, Sautebin, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901353/
https://www.ncbi.nlm.nih.gov/pubmed/17334599
http://dx.doi.org/10.1100/tsw.2007.34