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The Physiology of Obese-Hyperglycemic Mice [ob/ob Mice]
This review summarizes key aspects of what has been learned about the physiology of leptin deficiency as it can be observed in obese-hyperglycemic ob/ob mice. These mice lack functional leptin. They are grossly overweight and hyperphagic, particularly at young ages, and develop severe insulin resist...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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TheScientificWorldJOURNAL
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901356/ https://www.ncbi.nlm.nih.gov/pubmed/17619751 http://dx.doi.org/10.1100/tsw.2007.117 |