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Harnessing an RNA-mediated chaperone for the assembly of influenza hemagglutinin in an immunologically relevant conformation

A novel protein-folding function of RNA has been recognized, which can outperform previously known molecular chaperone proteins. The RNA as a molecular chaperone (chaperna) activity is intrinsic to some ribozymes and is operational during viral infections. Our purpose was to test whether influenza h...

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Detalles Bibliográficos
Autores principales: Yang, Seung Won, Jang, Yo Han, Kwon, Soon Bin, Lee, Yoon Jae, Chae, Wonil, Byun, Young Ho, Kim, Paul, Park, Chan, Lee, Young Jae, Kim, Choon Kang, Kim, Young Seok, Choi, Seong Il, Seong, Baik Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901386/
https://www.ncbi.nlm.nih.gov/pubmed/29295864
http://dx.doi.org/10.1096/fj.201700747RR