The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1

Mutations in PINK1, which impair its catalytic kinase activity, are causal for autosomal recessive early‐onset Parkinson's disease (PD). Various studies have indicated that the activation of PINK1 could be a useful strategy in treating neurodegenerative diseases, such as PD. Herein, it is shown...

Descripción completa

Detalles Bibliográficos
Autores principales: Barini, Erica, Miccoli, Ageo, Tinarelli, Federico, Mulholland, Katie, Kadri, Hachemi, Khanim, Farhat, Stojanovski, Laste, Read, Kevin D., Burness, Kerry, Blow, Julian J., Mehellou, Youcef, Muqit, Miratul M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901409/
https://www.ncbi.nlm.nih.gov/pubmed/29226533
http://dx.doi.org/10.1002/cbic.201700500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901409/
https://www.ncbi.nlm.nih.gov/pubmed/29226533
http://dx.doi.org/10.1002/cbic.201700500

Ejemplares similares