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Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability

BACKGROUND: The molecular characterization of endometrial cancer (EC) can facilitate identification of various tumor subtypes. Although EC patients with POLE mutations reproducibly demonstrate better prognosis, the outcome of patients with microsatellite instability (MSI) remains controversial. This...

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Detalles Bibliográficos
Autores principales: Haruma, Tomoko, Nagasaka, Takeshi, Nakamura, Keiichiro, Haraga, Junko, Nyuya, Akihiro, Nishida, Takeshi, Goel, Ajay, Masuyama, Hisashi, Hiramatsu, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901772/
https://www.ncbi.nlm.nih.gov/pubmed/29659608
http://dx.doi.org/10.1371/journal.pone.0195655