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Sensitivity to sequencing depth in single-cell cancer genomics
BACKGROUND: Querying cancer genomes at single-cell resolution is expected to provide a powerful framework to understand in detail the dynamics of cancer evolution. However, given the high costs currently associated with single-cell sequencing, together with the inevitable technical noise arising fro...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901877/ https://www.ncbi.nlm.nih.gov/pubmed/29661213 http://dx.doi.org/10.1186/s13073-018-0537-2 |