Structure of mammalian endolysosomal TRPML1 channel in nanodiscs

Transient receptor potential mucolipin 1 (TRPML1) is an endo/lysosomal cation channel ubiquitously expressed in mammalian cells(1,2) and its loss-of-function mutations are the direct cause of Type IV mucolipidosis (MLIV), an autosomal recessive lysosomal storage disease(3-6). Here we present the sin...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Qingfeng, She, Ji, Zeng, Weizhong, Guo, Jiangtao, Xu, Haoxing, Bai, Xiaochen, Jiang, Youxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901962/
https://www.ncbi.nlm.nih.gov/pubmed/29019981
http://dx.doi.org/10.1038/nature24035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901962/
https://www.ncbi.nlm.nih.gov/pubmed/29019981
http://dx.doi.org/10.1038/nature24035

Ejemplares similares