Cargando…
The Lysosomal Potassium Channel TMEM175 Adopts a Novel Tetrameric Architecture
TMEM175 is a lysosomal K(+) channel important for maintaining the lysosomal membrane potential and pH stability(1). It contains two homologous copies of a six-transmembrane (6-TM) domain, which has no sequence homology to the canonical tetrameric K(+) channels and lacks the TVGYG selectivity filter...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901963/ https://www.ncbi.nlm.nih.gov/pubmed/28723891 http://dx.doi.org/10.1038/nature23269 |