Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

Hybrid sterility is one of the reproductive isolation mechanisms leading to speciation. Prdm9, the only known vertebrate hybrid-sterility gene, causes failure of meiotic chromosome synapsis and infertility in male hybrids that are the offspring of two mouse subspecies. Within species, Prdm9 determin...

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Detalles Bibliográficos
Autores principales: Gregorova, Sona, Gergelits, Vaclav, Chvatalova, Irena, Bhattacharyya, Tanmoy, Valiskova, Barbora, Fotopulosova, Vladana, Jansa, Petr, Wiatrowska, Diana, Forejt, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902161/
https://www.ncbi.nlm.nih.gov/pubmed/29537370
http://dx.doi.org/10.7554/eLife.34282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902161/
https://www.ncbi.nlm.nih.gov/pubmed/29537370
http://dx.doi.org/10.7554/eLife.34282

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