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Mechanism and consequence of abnormal calcium homeostasis in Rett syndrome astrocytes

Astrocytes play an important role in Rett syndrome (RTT) disease progression. Although the non-cell-autonomous effect of RTT astrocytes on neurons was documented, cell-autonomous phenotypes and mechanisms within RTT astrocytes are not well understood. We report that spontaneous calcium activity is a...

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Detalles Bibliográficos
Autores principales: Dong, Qiping, Liu, Qing, Li, Ronghui, Wang, Anxin, Bu, Qian, Wang, Kuan Hong, Chang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902163/
https://www.ncbi.nlm.nih.gov/pubmed/29595472
http://dx.doi.org/10.7554/eLife.33417