A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach

Germline mutations in CDH1, the gene coding for the E-cadherin adhesion protein, are known to cause hereditary diffuse gastric cancer. We identified a new truncating germline mutation (p.Asp538Thrfs*19) in exon 11 of the CDH1 gene in a 41-year-old male with a diffuse gastric cancer. Although he had...

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Detalles Bibliográficos
Autores principales: Caggiari, Laura, Miolo, Gianmaria, Canzonieri, Vincenzo, De Zorzi, Mariangela, Alessandrini, Lara, Corona, Giuseppe, Cannizzaro, Renato, Santeufemia, Davide Adriano, Cossu, Antonio, Buonadonna, Angela, De Re, Valli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Bedside to Bench Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902241/
https://www.ncbi.nlm.nih.gov/pubmed/29131691
http://dx.doi.org/10.1080/15384047.2017.1394540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902241/
https://www.ncbi.nlm.nih.gov/pubmed/29131691
http://dx.doi.org/10.1080/15384047.2017.1394540

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