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The Hepatitis Delta Virus accumulation requires paraspeckle components and affects NEAT1 level and PSP1 localization

The Hepatitis Delta Virus (HDV) relies mainly on host proteins for its replication. We previously identified that PSF and p54nrb associate with the HDV RNA genome during viral replication. Together with PSP1, these proteins are part of paraspeckles, which are subnuclear bodies nucleated by the long...

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Detalles Bibliográficos
Autores principales: Beeharry, Yasnee, Goodrum, Gabrielle, Imperiale, Christian J., Pelchat, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902443/
https://www.ncbi.nlm.nih.gov/pubmed/29662142
http://dx.doi.org/10.1038/s41598-018-24500-1