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NIPS, a 3D network-integrated predictor of deleterious protein SAPs, and its application in cancer prognosis

Identifying deleterious mutations remains a challenge in cancer genome sequencing projects, reflecting the vast number of candidate mutations per tumour and the existence of interpatient heterogeneity. Based on a 3D protein interaction network profiled via large-scale cross-linking mass spectrometry...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Jing, Cheng, Xi, Zhou, Qiao, Yang, Jingxu, Zhang, Menghuan, Chen, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902451/
https://www.ncbi.nlm.nih.gov/pubmed/29662108
http://dx.doi.org/10.1038/s41598-018-24286-2