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NIPS, a 3D network-integrated predictor of deleterious protein SAPs, and its application in cancer prognosis
Identifying deleterious mutations remains a challenge in cancer genome sequencing projects, reflecting the vast number of candidate mutations per tumour and the existence of interpatient heterogeneity. Based on a 3D protein interaction network profiled via large-scale cross-linking mass spectrometry...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902451/ https://www.ncbi.nlm.nih.gov/pubmed/29662108 http://dx.doi.org/10.1038/s41598-018-24286-2 |