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In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design

Plants are extensively used in traditional medicine, and several plant antimicrobial peptides have been described as potential alternatives to conventional antibiotics. However, after more than four decades of research no plant antimicrobial peptide is currently used for treating bacterial infection...

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Detalles Bibliográficos
Autores principales: Porto, William F., Irazazabal, Luz, Alves, Eliane S. F., Ribeiro, Suzana M., Matos, Carolina O., Pires, Állan S., Fensterseifer, Isabel C. M., Miranda, Vivian J., Haney, Evan F., Humblot, Vincent, Torres, Marcelo D. T., Hancock, Robert E. W., Liao, Luciano M., Ladram, Ali, Lu, Timothy K., de la Fuente-Nunez, Cesar, Franco, Octavio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902452/
https://www.ncbi.nlm.nih.gov/pubmed/29662055
http://dx.doi.org/10.1038/s41467-018-03746-3