Synthesis of Symmetrical Tetrameric Conjugates of the Radiolanthanide Chelator DOTPI for Application in Endoradiotherapy by Means of Click Chemistry

Due to its 4 carbonic acid groups being available for bioconjugation, the cyclen tetraphosphinate chelator DOTPI, 1,4,7,10-tetraazacyclododecane-1,4,7, 10-tetrakis[methylene(2-carboxyethylphosphinic acid)], represents an ideal scaffold for synthesis of tetrameric bioconjugates for labeling with radi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wurzer, Alexander, Vágner, Adrienn, Horváth, Dávid, Fellegi, Flóra, Wester, Hans-Jürgen, Kálmán, Ferenc K., Notni, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902495/
https://www.ncbi.nlm.nih.gov/pubmed/29692987
http://dx.doi.org/10.3389/fchem.2018.00107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902495/
https://www.ncbi.nlm.nih.gov/pubmed/29692987
http://dx.doi.org/10.3389/fchem.2018.00107

Ejemplares similares