A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells

High-risk human papillomaviruses (HR-HPVs) are the causative agents for the onset of several epithelial cancers in humans. The deregulated expression of the viral oncoproteins E6 and E7 is the driving force sustaining the progression of malignant transformation in pre-neoplastic lesions. Targeting t...

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Detalles Bibliográficos
Autores principales: Messa, Lorenzo, Celegato, Marta, Bertagnin, Chiara, Mercorelli, Beatrice, Nannetti, Giulio, Palù, Giorgio, Loregian, Arianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902497/
https://www.ncbi.nlm.nih.gov/pubmed/29662081
http://dx.doi.org/10.1038/s41598-018-24470-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902497/
https://www.ncbi.nlm.nih.gov/pubmed/29662081
http://dx.doi.org/10.1038/s41598-018-24470-4

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