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The Long Non-coding RNA MEG3/miR-let-7c-5p Axis Regulates Ethanol-Induced Hepatic Steatosis and Apoptosis by Targeting NLRC5

Ethanol (EtOH)-induced hepatic injury, characterized by hepatic steatosis with apoptosis, causes heavy health burden personally and socially. Long non-coding RNAs (lncRNAs) have been implicated in liver diseases. However, the role of lncRNA maternally expressed gene 3 (MEG3) in EtOH-induced hepatic...

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Detalles Bibliográficos
Autores principales: Wang, Qin, Li, Mingfang, Shen, Zhiming, Bu, Fangtian, Yu, Haixia, Pan, Xueyin, Yang, Yang, Meng, Xiaoming, Huang, Cheng, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902529/
https://www.ncbi.nlm.nih.gov/pubmed/29692724
http://dx.doi.org/10.3389/fphar.2018.00302