Cargando…

Optineurin Functions for Optimal Immunity

Optineurin (OPTN) was identified 20 years ago in a yeast-two-hybrid screen with a viral protein known to inhibit the cytolytic effects of tumor necrosis factor. Since then, OPTN has been identified as a ubiquitin-binding protein involved in many signaling pathways and cellular processes, and mutatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Slowicka, Karolina, van Loo, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902560/
https://www.ncbi.nlm.nih.gov/pubmed/29692786
http://dx.doi.org/10.3389/fimmu.2018.00769