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Characterization of AiiK, an AHL lactonase, from Kurthia huakui LAM0618(T) and its application in quorum quenching on Pseudomonas aeruginosa PAO1

N-Acyl homoserine lactones (AHLs) act as the key quorum sensing (QS) signal molecules in gram-negative bacteria, which coordinates gene expression and then activates various processes, including biofilm formation and production of virulence factors in some pathogens. Quorum quenching (QQ), which is...

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Detalles Bibliográficos
Autores principales: Dong, Weiwei, Zhu, Jie, Guo, Xiang, Kong, Delong, Zhang, Qi, Zhou, Yiqing, Liu, Xiaoyang, Zhao, Shumiao, Ruan, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902575/
https://www.ncbi.nlm.nih.gov/pubmed/29662232
http://dx.doi.org/10.1038/s41598-018-24507-8