STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection

Cohesin is a multi-subunit nuclear protein complex that coordinates sister chromatid separation during cell division. Highly frequent somatic mutations in genes encoding core cohesin subunits have been reported in multiple cancer types. Here, using a genome-wide CRISPR-Cas9 screening approach to ide...

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Detalles Bibliográficos
Autores principales: Ding, Siyuan, Diep, Jonathan, Feng, Ningguo, Ren, Lili, Li, Bin, Ooi, Yaw Shin, Wang, Xin, Brulois, Kevin F., Yasukawa, Linda L., Li, Xingnan, Kuo, Calvin J., Solomon, David A., Carette, Jan E., Greenberg, Harry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902600/
https://www.ncbi.nlm.nih.gov/pubmed/29662124
http://dx.doi.org/10.1038/s41467-018-03782-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902600/
https://www.ncbi.nlm.nih.gov/pubmed/29662124
http://dx.doi.org/10.1038/s41467-018-03782-z

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