A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration

How cells move chemotactically remains a major unmet challenge in cell biology. Emerging evidence indicates that for interpreting noisy, shallow gradients of soluble cues a system must behave as an excitable process. Here, through an RNAi-based, high-content screening approach, we identify RAB35 as...

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Detalles Bibliográficos
Autores principales: Corallino, Salvatore, Malinverno, Chiara, Neumann, Beate, Tischer, Christian, Palamidessi, Andrea, Frittoli, Emanuela, Panagiotakopoulou, Magdalini, Disanza, Andrea, Malet-Engra, Gema, Nastaly, Paulina, Galli, Camilla, Luise, Chiara, Bertalot, Giovanni, Pece, Salvatore, Di Fiore, Pier Paolo, Gauthier, Nils, Ferrari, Aldo, Maiuri, Paolo, Scita, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902610/
https://www.ncbi.nlm.nih.gov/pubmed/29662076
http://dx.doi.org/10.1038/s41467-018-03571-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902610/
https://www.ncbi.nlm.nih.gov/pubmed/29662076
http://dx.doi.org/10.1038/s41467-018-03571-8

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