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Pan-cancer analysis of somatic mutations and transcriptomes reveals common functional gene clusters shared by multiple cancer types

To discover functional gene clusters across cancers, we performed a systematic pan-cancer analysis of 33 cancer types. We identified genes that were associated with somatic mutations and were the cores of a co-expression network. We found that multiple cancer types have relatively exclusive hub gene...

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Detalles Bibliográficos
Autores principales: Kim, Hyeongmin, Kim, Yong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902616/
https://www.ncbi.nlm.nih.gov/pubmed/29662161
http://dx.doi.org/10.1038/s41598-018-24379-y