A murine model of atopic dermatitis can be generated by painting the dorsal skin with hapten twice 14 days apart

Drug development involves pharmacometric experiments in animals. Such experiments should limit animal pain and stress. Conventional murine models of atopic dermatitis (AD) used in drug development are generated by weekly painting of hapten on dorsal skin for 5 weeks. The present study aimed to devel...

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Detalles Bibliográficos
Autores principales: Kitamura, Ayaka, Takata, Ryohei, Aizawa, Shin, Watanabe, Hajime, Wada, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902631/
https://www.ncbi.nlm.nih.gov/pubmed/29662233
http://dx.doi.org/10.1038/s41598-018-24363-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902631/
https://www.ncbi.nlm.nih.gov/pubmed/29662233
http://dx.doi.org/10.1038/s41598-018-24363-6

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