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A murine model of atopic dermatitis can be generated by painting the dorsal skin with hapten twice 14 days apart
Drug development involves pharmacometric experiments in animals. Such experiments should limit animal pain and stress. Conventional murine models of atopic dermatitis (AD) used in drug development are generated by weekly painting of hapten on dorsal skin for 5 weeks. The present study aimed to devel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902631/ https://www.ncbi.nlm.nih.gov/pubmed/29662233 http://dx.doi.org/10.1038/s41598-018-24363-6 |