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CGA-N12, a peptide derived from chromogranin A, promotes apoptosis of Candida tropicalis by attenuating mitochondrial functions

CGA-N12 (the amino acid sequence from the 65th to the 76th residue of the N-terminus of chromagranin A) is an antifungal peptide derived from human chromogranin A (CGA). In our previous investigation, CGA-N12 was found to have specific anti-candidal activity, though the mechanism of action remained...

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Detalles Bibliográficos
Autores principales: Li, Ruifang, Zhang, Ruiling, Yang, Yanhui, Wang, Xueqin, Yi, Yanjie, Fan, Pei, Liu, Zhengwei, Chen, Chen, Chang, Junpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902677/
https://www.ncbi.nlm.nih.gov/pubmed/29559502
http://dx.doi.org/10.1042/BCJ20170894