Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity

The standard treatment for chronic obstructive pulmonary disease is a combination of anti-inflammatory drugs and bronchodilators. We recently found that mepenzolate bromide (MP), an antagonist for human muscarinic M3 receptor (hM(3)R), has both anti-inflammatory and short-acting bronchodilatory acti...

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Detalles Bibliográficos
Autores principales: Tanaka, Ken-Ichiro, Yamakawa, Naoki, Yamashita, Yasunobu, Asano, Teita, Kanda, Yuki, Takafuji, Ayaka, Kawahara, Masahiro, Takenaga, Mitsuko, Fukunishi, Yoshifumi, Mizushima, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902689/
https://www.ncbi.nlm.nih.gov/pubmed/29692733
http://dx.doi.org/10.3389/fphar.2018.00344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902689/
https://www.ncbi.nlm.nih.gov/pubmed/29692733
http://dx.doi.org/10.3389/fphar.2018.00344

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