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1000 human genomes carry widespread signatures of GC biased gene conversion

BACKGROUND: GC-Biased Gene Conversion (gBGC) is one of the important theories put forward to explain profound long-range non-randomness in nucleotide compositions along mammalian chromosomes. Nucleotide changes due to gBGC are hard to distinguish from regular mutations. Here, we present an algorithm...

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Detalles Bibliográficos
Autores principales: Dutta, Rajib, Saha-Mandal, Arnab, Cheng, Xi, Qiu, Shuhao, Serpen, Jasmine, Fedorova, Larisa, Fedorov, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902838/
https://www.ncbi.nlm.nih.gov/pubmed/29661137
http://dx.doi.org/10.1186/s12864-018-4593-1