Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing

BACKGROUND: Accumulating evidence suggests alternative splicing (AS) is a co-transcriptional splicing process not only controlled by RNA-binding splicing factors, but also mediated by epigenetic regulators, such as chromatin structure, nucleosome density, and histone modification. Aberrant AS plays...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Tianbao, Liu, Qi, Garza, Nick, Kornblau, Steven, Jin, Victor X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902843/
https://www.ncbi.nlm.nih.gov/pubmed/29665865
http://dx.doi.org/10.1186/s13073-018-0538-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902843/
https://www.ncbi.nlm.nih.gov/pubmed/29665865
http://dx.doi.org/10.1186/s13073-018-0538-1

Ejemplares similares