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Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing
BACKGROUND: Accumulating evidence suggests alternative splicing (AS) is a co-transcriptional splicing process not only controlled by RNA-binding splicing factors, but also mediated by epigenetic regulators, such as chromatin structure, nucleosome density, and histone modification. Aberrant AS plays...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902843/ https://www.ncbi.nlm.nih.gov/pubmed/29665865 http://dx.doi.org/10.1186/s13073-018-0538-1 |