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The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells

BACKGROUND: Multiple trials have attempted to demonstrate the effective induction of cell death in TRAIL-resistant cancer cells, including using a combined treatment of recombinant TRAIL and various proteasome inhibitors. These studies have yielded limited success, as the mechanism of cell death is...

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Detalles Bibliográficos
Autores principales: Ryu, Sunhyo, Ahn, Yun Jeong, Yoon, Chakeong, Chang, Jeong Hwan, Park, Yoonkyung, Kim, Tae-Hyoung, Howland, Amanda R., Armstrong, Cheryl A., Song, Peter I., Moon, Ae Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902847/
https://www.ncbi.nlm.nih.gov/pubmed/29661248
http://dx.doi.org/10.1186/s12885-018-4352-3