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Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study

BACKGROUND: Sepsis remains a major cause of mortality in critical care, for which specific treatments are lacking. The dysregulated response to infection seen in sepsis includes features of lymphocyte dysfunction and exhaustion, suggesting that immune-stimulatory therapy may improve outcomes in cert...

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Detalles Bibliográficos
Autores principales: Wilson, Julie K., Zhao, Yuan, Singer, Mervyn, Spencer, Jo, Shankar-Hari, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902875/
https://www.ncbi.nlm.nih.gov/pubmed/29661225
http://dx.doi.org/10.1186/s13054-018-2020-2