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Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study
BACKGROUND: Sepsis remains a major cause of mortality in critical care, for which specific treatments are lacking. The dysregulated response to infection seen in sepsis includes features of lymphocyte dysfunction and exhaustion, suggesting that immune-stimulatory therapy may improve outcomes in cert...
Autores principales: | Wilson, Julie K., Zhao, Yuan, Singer, Mervyn, Spencer, Jo, Shankar-Hari, Manu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902875/ https://www.ncbi.nlm.nih.gov/pubmed/29661225 http://dx.doi.org/10.1186/s13054-018-2020-2 |
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