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A Coxiella burnetii phospholipase A homolog pldA is required for optimal growth in macrophages and developmental form lipid remodeling

BACKGROUND: Many gram-negative bacteria produce an outer membrane phospholipase A (PldA) that plays an important role in outer membrane function and is associated with virulence. RESULTS: In the current study, we characterized a pldA mutant of Coxiella burnetii, an intracellular gram-negative pathog...

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Detalles Bibliográficos
Autores principales: Stead, Christopher M., Cockrell, Diane C., Beare, Paul A., Miller, Heather E., Heinzen, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902883/
https://www.ncbi.nlm.nih.gov/pubmed/29661138
http://dx.doi.org/10.1186/s12866-018-1181-0